An extensively glycosylated archaeal pilus survives extreme conditions
نویسندگان
چکیده
منابع مشابه
An archaeal tRNA-synthetase complex that enhances aminoacylation under extreme conditions.
Aminoacyl-tRNA synthetases (aaRSs) play an integral role in protein synthesis, functioning to attach the correct amino acid with its cognate tRNA molecule. AaRSs are known to associate into higher-order multi-aminoacyl-tRNA synthetase complexes (MSC) involved in archaeal and eukaryotic translation, although the precise biological role remains largely unknown. To gain further insights into archa...
متن کاملEntanglement's benefit survives an entanglement-breaking channel.
Entanglement is essential to many quantum information applications, but it is easily destroyed by quantum decoherence arising from interaction with the environment. We report the first experimental demonstration of an entanglement-based protocol that is resilient to loss and noise which destroy entanglement. Specifically, despite channel noise 8.3 dB beyond the threshold for entanglement breaki...
متن کاملExtreme Deviations from Expected Evolutionary Rates in Archaeal Protein Families
Origin of new biological functions is a complex phenomenon ranging from single-nucleotide substitutions to the gain of new genes via horizontal gene transfer or duplication. Neofunctionalization and subfunctionalization of proteins is often attributed to the emergence of paralogs that are subject to relaxed purifying selection or positive selection and thus evolve at accelerated rates. Such phe...
متن کاملcGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV‐1 envelope glycoprotein vaccine candidate
We describe the properties of BG505 SOSIP.664 HIV-1 envelope glycoprotein trimers produced under current Good Manufacturing Practice (cGMP) conditions. These proteins are the first of a new generation of native-like trimers that are the basis for many structure-guided immunogen development programs aimed at devising how to induce broadly neutralizing antibodies (bNAbs) to HIV-1 by vaccination. ...
متن کاملAn archaeal iron-oxidizing extreme acidophile important in acid mine drainage.
A new species of Archaea grows at pH approximately 0.5 and approximately 40 degrees C in slime streamers and attached to pyrite surfaces at a sulfide ore body, Iron Mountain, California. This iron-oxidizing Archaeon is capable of growth at pH 0. This species represents a dominant prokaryote in the environment studied (slimes and sediments) and constituted up to 85% of the microbial community wh...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Microbiology
سال: 2019
ISSN: 2058-5276
DOI: 10.1038/s41564-019-0458-x